Woman in a kitchen with Cellova Health L-Methylfolate

Active folate that reaches your cells. From €1,99 a day.

The Cellova kit: L-Methylfolate⁺, Advanced B-Complex and TMG⁺ — the three forms your body uses immediately, no processing needed. Subscribe and save 10%, with free shipping.

4.8 · 274 reviews

Why methylated folate is in the protocols of the world's top practitioners.

  • 60-day guarantee
  • Tested quality
Free EU shipping over €100
Formulated by physicians
Clinically proven
Tested quality
Vegan
No fillers, non-GMO

The kit

One protocol instead of three separate supplements.

L-Methylfolate⁺, Advanced B-Complex and TMG⁺ cover the whole methylation cycle: the active folate, the cofactors that drive it, and the betaine for the second pathway. One protocol, instead of three brands in the cupboard.

  • 60-day guarantee
  • No fillers, non-GMO
The three Cellova Health formulas on a podium

Why the active form

With an MTHFR variant, folic acid never reaches the cells.

Over 50% of people carry an MTHFR gene variant that slows the conversion of folic acid into a usable form. L-Methylfolate is already in the active 5-MTHF form, so the body uses it immediately — that step never happens.

  • Tested quality
  • Formulated by physicians
Diagram of the MTHFR gene and folate conversion

From published studies

What the studies on active folate show

30%
Lower homocysteinewith 3 months of use
126%
Greater enduranceunder physical load
36%
More repsin strength training
32%
Response in depressionin SSRI-resistant patients

Studies on L-methylfolate and methylated B vitamins: Molecular Vision 2020 · International Journal of Medical Sciences 2023 · PMC-indexed 2022 · American Journal of Psychiatry 2012.

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The benefits for body and mind

Woman holding a Cellova Health capsule
For the body
Heart health Balances homocysteine to keep arteries flexible and blood pressure in a healthy range.
Cellular energy Plays a direct role in methylation and ATP generation — fueling your body's energy production.
DNA repair Supplies the folate cofactor for nucleotide synthesis and healthy cell turnover.
Nervous system Feeds the central and peripheral nervous systems with active folate, straight to the tissue.
Immune modulation Supports normal white-blood-cell formation and the regulation of inflammation.
Detox Fuels the methylation pathways that clear hormones, toxins and heavy metals through the liver.
For the mind
Mood balance Supports healthy serotonin, dopamine and norepinephrine levels for emotional stability.
Focus and clarity Optimizes the neurotransmitter signaling behind cognitive function.
Sleep quality Supports natural melatonin production for better sleep.
Stress resilience Reduces the homocysteine spikes that amplify cortisol responses.
Mental energy Improves cerebral blood flow and ATP production in brain tissue.
Better memory Donates the methyl groups key to the brain functions behind memory.

Start the whole protocol today.

4.8 (274 reviews)

For best results, take it for at least 3 months.

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How many packs?

−10% for 2 packs, applied at checkout

60-day guarantee · 4.8★ from 274 reviews

Overview & benefits

50% of people carry an MTHFR gene variant that blocks the last step of folate activation. When that happens, methylation slows and everything — mood, detox, energy production — suffers. L-Methylfolate⁺ gives you the fully active form of vitamin B9, ready to use the moment it reaches your bloodstream. Combined with the right B vitamins and betaine (TMG), the effects are strongest. ✔ Supports proper methylation for detox, DNA repair and cellular resilience ✔ Promotes healthy neurotransmitter synthesis (serotonin, dopamine, norepinephrine) ✔ Overcomes the folate-absorption problems tied to MTHFR variants ✔ Backed by physicians, genetic labs and clinical practitioners ✔ A potent, filler-free formula — third-party tested. 5 mg pure L-methylfolate — an advanced formula for homocysteine control, steadier mood, nervous-system support and higher metabolic demand.

Ingredients

L-Methylfolate 5 mg: 5 mg L-methylfolate (from 7.1 mg calcium salt of L-5-methylfolate) · 255 mg glycine — supports stability and absorption · Plant cellulose (capsule), microcrystalline cellulose — Advanced B-Complex: Vitamin C (as ascorbyl palmitate) – 15 mg (17%) · Thiamine (B1) – 25 mg · Riboflavin 5'-phosphate (B2) – 25 mg · Niacinamide (B3) – 150 mg NE · Vitamin B6 (pyridoxine HCl + P5P) – 55 mg · Vitamin B12 (methylcobalamin) – 1,000 µg · Biotin – 400 µg · Pantothenic acid (B5) – 150 mg · Choline (bitartrate) – 50 mg · Inositol – 50 mg · PABA – 50 mg · Plant cellulose (capsule), microcrystalline cellulose — TMG Betaine (2 capsules): 1000 mg trimethylglycine (anhydrous betaine) · 5 mg zinc (zinc picolinate) · Plant cellulose (capsule), microcrystalline cellulose — What it doesn't contain: No synthetic folic acid. No magnesium stearate. No gluten, soy, dairy, nuts, eggs, excipients, preservatives or artificial fillers. Made in a GMP-compliant facility. Third-party tested for purity, potency and heavy metals.

Tested quality

Every ingredient and dose in Cellova Health supplements is third-party tested. That process guarantees what you see on the label is 100% what you get. In other words, you know exactly what your body is taking.

How to take

One Methylfolate capsule, one B-vitamin capsule, and 2 Betaine capsules a day. We recommend mornings, so you don't forget. But any time works, with or without food.

Storage

Store in a cool, dry place away from direct sunlight — no fridge needed.

The benefits of healthy methylation build over time

The daily Cellova ritual — a capsule, water and morning light
  1. Week 1

    Fill in what's missing

    As the gaps close, you'll notice steadier daily energy and a more balanced mood.

  2. Week 2

    Clarity comes back

    Improved neurotransmitter function brings better focus, stronger motivation and steadier brain performance.

  3. Week 3

    Mental lift and resilience

    Better emotional and physical stamina, less overwhelm, and a clearer, more engaged mind.

  4. Month 1

    Whole-body recalibration

    Methylation cycles stabilize. The nervous system, cardiovascular function and your sleep-and-recovery rhythm start to sync up.

  5. Month 2 and beyond

    Long-term activation

    Mood, cognition and cardiovascular function keep improving. Long-term folate intake settles methylation, detox and brain support into a rhythm.

From €1,99 a day | 60-day guarantee

Customer reviews

What customers say

4.8 out of 5 4.8 out of 5 from 274 reviews

Rating breakdown Filter

What customers rate

Mood balance4.8

Physical health4.76

Value4.22

What customers say

  • 97% of reviewers rated it four stars or higher.
  • Most talked about: energy, everyday, mood.
  • Mood balance scores highest, at 4.8 out of 5.
  • 214 of 274 reviews come from a verified purchase.

Summary generated from 274 customer reviews.

Filter by topic

Showing 6 of 274 reviews

5 out of 53 months ago

I decided to take them for two months before booking my bloods so I'd have something to compare against. The numbers came back in order and I've moved to the subscription so I don't have to think about it.

Mood balance5 out of 5Body health5 out of 5Value for money5 out of 5
Reneta R.Verified purchase
5 out of 53 months ago

Two months of nothing, and if I hadn't paid for three up front I'd have quit. Month three brought sleep, month four energy, and by month five my head cleared. Patience was the whole trick.

Mood balance5 out of 5Body health5 out of 5Value for money4 out of 5
Valentin Zh.Verified purchase
5 out of 53 months ago

Bought the set because I was fed up ordering three different bottles from three different places. Turns out they also work better together than they did separately. Works out cheaper a month as well.

Mood balance5 out of 5Body health5 out of 5Value for money5 out of 5
Antonia Zh.Verified purchase
5 out of 53 months ago

Before we started trying, my gynaecologist told me to drop the ordinary folic acid and move to the active form. I took the bundle so all three came from one place. I'm on month five and I'm not planning to change.

Mood balance5 out of 5Body health5 out of 5Value for money4 out of 5
Desislava T.
5 out of 54 months ago

I'm in the gym five times a week and what I was after was quicker recovery. For six weeks now I'm not dragging my legs the next day and the last sets go easier.

Mood balance5 out of 5Body health5 out of 5Value for money4 out of 5
Todor B.Verified purchase
5 out of 54 months ago

I had trouble sleeping and a fair bit of anxiety, and honestly I didn't believe vitamins would do anything. Turns out I was wrong. I'm in my third month and something new keeps showing up each month.

Mood balance5 out of 5Body health5 out of 5Value for money5 out of 5
Lachezar B.Verified purchase

What the leading experts say

Why healthy methylation is in the protocols of the world's best:

Gary Brecka
Gary BreckaHUMAN BIOLOGIST, ULTIMATE HUMAN PODCAST
Up to 60% of the population has an MTHFR gene mutation. That means you CANNOT process folic acid effectively. You need methylfolate.
Dr. Ben Lynch
Dr. Ben LynchNATUROPATHIC PHYSICIAN, AUTHOR OF "DIRTY GENES"
Folic acid is basically a square wheel to your body. It has to be processed by many different enzymes so your body can turn it into a round wheel — L-methylfolate.
Dave Asprey
Dave AspreyFOUNDER OF BULLETPROOF, "THE FATHER OF BIOHACKING"
Methylfolate and methyl B12 work together to control methylation reactions that regenerate your DNA and brain cells.
Dr. Rhonda Patrick
Dr. Rhonda PatrickBIOCHEMIST, FOUNDMYFITNESS
People with MTHFR mutations have a significantly higher risk of depression, anxiety and cognitive decline — all of which can improve with the right methylated supplementation.
Andrew Huberman
Andrew HubermanNEUROSCIENTIST, STANFORD UNIVERSITY, HUBERMAN LAB PODCAST
Methylfolate is the main circulating form of folate, used to produce serotonin, dopamine and norepinephrine.
Dr. Mark Hyman
Dr. Mark HymanFUNCTIONAL MEDICINE PIONEER, CLEVELAND CLINIC
Optimizing methylation with the right forms of B vitamins is one of the most powerful interventions in functional medicine.
Dr. Chris Masterjohn
Dr. Chris MasterjohnNUTRITIONAL SCIENCES PHD
Homocysteine is one of the best markers of methylation status. If it's above 10 µmol/L, you have a problem worth addressing.
Bryan Johnson
Bryan JohnsonFOUNDER OF BLUEPRINT PROTOCOL, "DON'T DIE" MOVEMENT
Methylation is one of the key markers I track in Blueprint. It's measurable, it's optimizable, and it's critical for longevity.
Dr. Terry Wahls
Dr. Terry WahlsCLINICAL PROFESSOR, UNIVERSITY OF IOWA
For my patients with autoimmune conditions and multiple sclerosis, optimizing methylation with methylated B vitamins is a critical part of the protocol.
Tim Ferriss
Tim FerrissTHE 4-HOUR WORK WEEK PODCAST
These days I don't take many supplements. But B12 and methylfolate are non-negotiable for me, for their key role in homocysteine control and longevity.

Why Cellova

A cleaner formula, a better form, a real result.

Cellova Ordinary supplements
Active form5-MTHF, ready to work immediately
Clinical dosesthe doses from the clinical studies
Third-party testedan independent lab for purity
No fillersno GMO, dyes or allergens
60-day guaranteemoney back, no questions

Разликата е в молекулата.

Try it for 60 days, risk-free

You'll sleep, function and feel better within 60 days. Or we simply give you your money back — even if you return empty bottles.

Try the kit

≈ €1,99 a day | 60-day guarantee

A family in the kitchen with Cellova Health formulas

Frequently asked questions

What is methylation?

The process your cells use to produce energy, repair DNA and balance hormones. It happens 300 billion times a day — and it depends on folate.

When will I feel it?

Most people feel more energy and clearer focus within 2–4 weeks. Consistency delivers the result.

What makes active folate better?

5-MTHF is the form the cell uses directly. Regular folic acid has to be converted first — and over half of people do that slowly.

Is it safe to take daily?

Yes. 5-MTHF is the form of folate your body uses naturally. Vegan capsule, no fillers, in the doses from the clinical studies.

How does the 60-day guarantee work?

You have 60 days to try the formula. Return the bottle within that window and you get your money back — even if it's empty.

How much is shipping?

We ship across the EU. Free over €100 — the rate and delivery time show at checkout.